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Ideas

Vaccination

Protecting a person against smallpox with matter from a cowpox sore, which Edward Jenner showed in 1796; the word comes from Latin vacca, “cow.”

Instructions for Vaccine Inoculation

Edward Jenner, Instructions for Vaccine Inoculation (London: D. N. Shury, 1801) · about 1799–1801 (catalogued as 1801)

1

Let the vaccine fluid be taken, for the purpose of Inoculation, from a pustule that is making its progress regularly, and which possesses the true vaccine character, on any day from the fifth to the eighth, or even a day or two later, provided the efflorescence be not then formed around it. When the efflorescence is formed, it is always most prudent to desist from taking any more of the virus from that pustule.

Let the vaccine fluid be taken, for the purpose of inoculation, from a pustule that is making its progress regularly, and which possesses the true vaccine character, on any day from the fifth to the eighth, or even a day or two later, provided the efflorescence be not then formed around it. When the efflorescence is formed, it is always most prudent to desist from taking any more of the virus from that pustule.

7

A little practice in vaccine inoculation, attentively conducted, impresses on the mind the perfect character of the vaccine pustule; therefore, when a deviation arises, of whatever kind it may be, common prudence points out the necessity of re-inoculation, first, with vaccine virus of the most active kind, and secondly, should this be ineffectual, with variolous virus. But if the constitution shews an insusceptibility of one, it commonly does of the other.

A little practice in vaccine inoculation, attentively conducted, impresses on the mind the perfect character of the vaccine pustule. Therefore, when a deviation arises, of whatever kind it may be, common prudence points out the necessity of reinoculation: first, with vaccine virus of the most active kind, and secondly, should this be ineffectual, with variolous virus. But if the constitution shows an insusceptibility of one, it commonly does of the other.