Chalco
A town and region southeast of Mexico-Tenochtitlan, on the shore of Lake Chalco, which the smallpox reached after the city.
Today: Chalco, State of Mexico, Mexico
The Smallpox in Mexico, 1520
Bernardino de Sahagún and his Nahua informants, History of the Conquest of Mexico (Book XII of the General History of the Things of New Spain), edited by Carlos María de Bustamante (1829) · compiled from the 1550s to the 1570s (events of 1520–1521)
Esta pestilencia mató gentes sin número, muchas murieron de hambre porque no habia quien pudiese hacer comida: los que escaparon de esta pestilencia quedaron con las caras ahoyadas, y algunos los ojos quebrados; duró la fuerza de esta pestilencia sesenta dias, y después que fue aflojando en México, fue hacia Chalco.
This pestilence killed countless people. Many died of hunger, because no one was left who could make food. Those who escaped it were left with pitted faces, and some with broken eyes. The pestilence raged for sixty days. After it began to ease in Mexico, it moved on toward Chalco.