Planting Smallpox
- Written
- 1742 (this copy about 1778)
- Place
- Beijing
- Language
- Classical Chinese
- Kind of source
- medical
- Reading time
- 8 minutes
- Difficulty
- Challenging
- Intensity
- Low: sick children, pustules, and scabs described plainly; no deaths described
SmallpoxInoculation and vaccinationDoctors and medical ideas
Once in a Lifetime themes: Unknowns
To give a healthy child smallpox on purpose, a doctor ground the dry scabs of a mild case very fine, put the powder in the end of a bent silver tube, and blew it into the child’s nostril, the left for a boy and the right for a girl. By the seventh day the child had a fever.
This passage opens the book on planting smallpox in the Golden Mirror of Medicine (Yizong jinjian), a large medical compendium ordered by the Qianlong emperor in 1739, compiled under the court physicians Wu Qian and Liu Yuduo, and completed in 1742. It was meant to set a standard: teachers of medicine were to teach from it and students to learn from it. Planting smallpox was the Chinese form of what historians call inoculation or variolation.
The editors knew nothing of viruses. They explained smallpox as a “fetal poison” that every child carried from the womb, and they thought planting worked because the scab’s qi drew that poison out gently, on a day when the child was well. They admit that the method’s origin was known only from a legend and that it had been taught mostly by word of mouth.
This is an official text written to teach and persuade. It shows what the court’s doctors recommended, not how every practitioner worked; the editors themselves say the dry method was much used in their day, though they preferred the water method. The copy translated here was made for the imperial library in about 1778.
Watch for how they explain why planting works, and for their judgment of each of the four methods, including one they call cruel.
What we know now
No record from the Song dynasty supports the story of the holy man of Mount Emei. Historians can trace planting smallpox securely only to the Ming dynasty, between the late fifteenth and the late sixteenth century, in Jiangxi and Anhui, from where it spread through the Yangtze valley (Ch’iu 2006; Guan et al. 2026).
The Kangxi emperor brought planting into the palace in 1678 and had it carried to Mongolia. The method first appeared in a printed medical book in 1713, and the many reprints of the Golden Mirror spread it further. Officials were never ordered to promote it, and by the early nineteenth century it was still used mostly by better-off families, more in the south than the north (Ch’iu 2006).
Smallpox is caused by a virus that usually enters through the nose and throat; it can also be found in scabs. Planting gave a real infection, usually milder than the natural disease: estimates put deaths after planting at about 0.5–2 percent, against about 30 percent for natural smallpox. A planted child could also pass smallpox on to others (Guan et al. 2026). Vaccination with cowpox, which carried no such risk, was brought to Canton by Alexander Pearson in 1805 (Lockhart 1861).
Read alongside
- Engrafting against Smallpox
Lady Mary Wortley Montagu watched old women in Ottoman Adrianople give children smallpox in 1717, through small cuts rather than the nose. Compare who performs the operation in each source, when in the year it is done, and how each writer explains why it is safe.
- Instructions for Vaccine Inoculation
Edward Jenner, in 1801, tells doctors how to take cowpox matter and put it into a scratch on the arm. Compare how carefully each text chooses its matter, what signs each watches for, and what each says to do when the operation does not take.
The edited translation, in simplified modern English. Bracketed words were added for clarity; [...] marks a cut. Tap a note number to read the note.
Introduction
Smallpox is a fetal poison.1 It lies hidden in the body from the moment the body takes shape, and it breaks out when something sets it off. No one born can escape it. It may break out when a child catches a seasonal qi,2 or is chilled by wind and cold, or from food and drink, or from a fright. One illness leads to another, the harm takes many forms, and its changes cannot be foreseen. Besides, few cases go smoothly and many are dangerous. In some, a thousand remedies and a hundred plans cannot give one chance in ten thousand of recovery. That is why it is so hard [to treat]. In the past there was a method of planting smallpox.3 It began in Jiangyou4 and spread to the capital region. As for where it came from, people tell a story from the time of Emperor Zhenzong of the Song.5 A holy man came out of Mount Emei6 and planted smallpox in the son of the chancellor Wang Dan, and the boy recovered. From then on it was handed down in the world. The story may seem far-fetched. But judged by reason, the method truly helps [Heaven and Earth] in their work of creating and nourishing life, and it wisely suits the treatment to the time. Natural smallpox is caught after one falls ill, but planted smallpox is given before any illness. Natural smallpox is treated when the illness has already taken hold, but planted smallpox is managed on a day when the child is well. [The seed's qi] passes inward from the surface, and [the poison] comes back out from inside to the surface. No other illnesses are mixed in, and good prescriptions guide it from outside. Steamed out little by little, the fetal poison comes out completely. Then why fear harm of many kinds and changes no one can foresee, which leave good doctors helpless? This is truly a fine method for leaving danger behind and walking on level ground, for avoiding peril and reaching safety. But planting smallpox has mostly been taught by word of mouth, from teacher to pupil, and medical books have not recorded it. We fear that later generations will take it for empty, foolish talk. If this goes on for long, there will be nothing to check it against. Then this perfect principle and good method will be cast aside as useless, and its wonderful power will be lost. Would that not be a great pity? So we have studied the method of planting smallpox in detail, weighed it carefully and precisely, and compiled it into a book to hand down for a thousand ages. We hope it will be a bridge for those who plant smallpox, and bring every infant safely to a long life.
Essentials of Planting Smallpox
We have looked into the methods of planting smallpox. Some take the fluid from the pustules and plant that. Some dress a child in the clothes of a child with smallpox. Some grind the scabs to powder and blow it dry into the nose; this is called the dry seed.7 Some moisten the scab powder and put it into the nostril; this is called the water seed. Comparing the four, the water seed is best and the dry seed next. Smallpox clothes usually do not take, and smallpox fluid is too cruel. So the old method used only the water seed, because it is gentle and safe. In recent times people began to use the dry seed. It is quick and direct, but it is felt to be a little too fast and violent. As for smallpox clothes and smallpox fluid, those methods must never be followed. The water seed is good because it acts very gently. Neither fast nor slow, it enters little by little. After it is planted, the child suffers no harm, and the fetal poison has a chance to come out gradually. It succeeds every time, as surely as a shadow follows a body or an echo a sound. It is perfect in every way, a method to follow and hand down, the best way of planting smallpox. Next comes the dry seed. It is violent, but still close to the water-seed method, and it may be used if the child is strong and sturdy.
The Water Seed Method
[...] At the time of planting, examine the child closely. Its qi and blood must be in harmony and its organs in balance. Inside, it must not be troubled by phlegm, heat, or undigested food. Outside, it must not be under attack from the qi of the six excesses.8 Only then plant it, using the best scabs. For a child of one year, use twenty-some pieces of scab; for a child of three or four, thirty-some. Put them in a clean porcelain cup and grind them to a fine powder with a willow-wood pestle. Drip three to five drops of clean water into the cup, warm in spring and hot in winter. If the mixture is dry, add a few drops more. What matters is to mix it evenly, neither dry nor wet. Spread a little new cotton into a very thin sheet, wrap the mixed scab powder in it, and pinch it into the shape of a jujube pit. Tie it with red thread, leaving about an inch9 of thread, and cut off the rest. Put the seed into the nostril, the left for a boy and the right for a girl.10 Someone must stay with the child and watch it all the time. If the child plays with the seed, stop it at once. If the child sneezes it out, put it back in the nose at once, without the least delay, or the seed’s qi may leak away. Once the seed is in, leave it for six double hours,11 then take it out. In bitter cold, leave it in a little longer; in mild, warm weather, it may come out a little earlier. The point is to judge at the time. After the seed is taken out, its qi enters little by little and passes through all five organs.12 On the seventh day, fever begins. After three days of fever, the spots appear. Three days later, all the spots are out. Three days after that, they fill with fluid. Three days after they are full, the fluid dries up and they form scabs, and the great work is done.
The Dry Seed Method
[...] For the dry-seed method, use a silver tube about five or six inches long, bent near the end. Grind the smallpox scabs very fine and put the powder in the end of the tube. Aim it carefully at the nostril, the left for a boy and the right for a girl, and blow the powder in. By the seventh day there is fever, [as with the water seed]. Many people use this method nowadays. It is simple and quick, and the seed cannot fall out and let its qi escape. But we fear that later people will use it badly. Blown too lightly, the powder does not go in at once; blown too hard, it acts too fast and violently for the child to bear. Then too, if the nose runs too much, the seed washes out with the mucus, and often it does not take. Since we wish to hand down a method to later ages, we should choose the gentle, safe, and wholly reliable one and follow it. That is why we choose only the water seed.
The Smallpox Clothes Method
When a child with smallpox reaches the stage when the pustules fill with fluid, and they are full, its smallpox qi is at its strongest. Take the shirt that child wears next to the skin, and have a boy or girl who has not had smallpox wear it for two or three days, without taking it off at night. On the ninth or eleventh day, fever begins. This is passing it on by clothing. But we fear the qi may be too thin to get through. Often there is no fever and no pox comes out. The method is unreliable, so it must not be used.
The Smallpox Fluid Method
Choose a child whose smallpox is going smoothly. Wipe up the fluid from its pustules with cotton, and put the cotton into the nose, the left for a boy and the right for a girl. This too can bring out the pox. But when they take the fluid, people pinch the pustules open without the family knowing, and steal it to use as seed. This lets the sick child’s true qi leak out, so that its poison cannot be cleared. It is a cruel, wrong, and inhumane thing to do. All who agree with us should hate it deeply and put a complete stop to it. How could anyone condemn it and then do it himself?
Notes
- Chinese doctors held that smallpox came from a poison every child received in the womb. It lay hidden until something drew it out, and the illness then drove it from the body. back
- Qi was the vital breath or energy that Chinese thinkers saw in the body and in the world. A seasonal qi was a harmful influence of the weather at a given time of year. back
- 種痘 zhongdou: giving a healthy child smallpox on purpose, from the scabs or fluid of a mild case, so that it would have a milder illness and never catch the disease again. back
- Jiangxi province, in southeastern China. back
- Zhenzong reigned 997–1022, more than seven hundred years before this book. Wang Dan (957–1017) was his chief minister. back
- One of the four sacred mountains of Chinese Buddhism, in Sichuan, in western China. back
- 苗 miao, literally “sprout” or “seedling”: the matter used to plant the pox, usually scabs from a child with a mild case. back
- The six excesses were wind, cold, summer heat, damp, dryness, and fire: kinds of harmful qi from the weather that doctors thought could invade the body from outside. back
- Chinese inches (cun). A Qing cun was a little longer than an English inch. back
- The left side belonged to yang and to males, the right to yin and to females, so boys and girls were treated on opposite sides. back
- The Chinese day was divided into twelve double hours (shichen), so six double hours made half a day. back
- The five organs were the heart, liver, spleen, lungs, and kidneys. The next section of the book, left out here, traces the seed’s qi from the nose to the lungs and on through the other four. back
夫痘胎毒也伏於有形之始因感而𤼵為生人所不能免然其𤼵也或染時氣或感風寒或因飲食或由驚恐以病引病為患多端變更莫測且其間順吉者少險逆者多有千方百計而不能冀其愈於萬一者此其所以為難也
Now smallpox is fetal poison. It lies hidden from the beginning of having form; owing to being affected [by something], it breaks out; it is what living people cannot avoid. But its breaking out: either one is infected by seasonal qi, or affected by wind and cold, or owing to food and drink, or from fright; illness drawing out illness, the harm is of many kinds, its changes unfathomable. Moreover among [cases], the smooth and auspicious are few, the dangerous and adverse many; there are those for whom a thousand prescriptions and a hundred plans cannot hope for recovery in one out of ten thousand. This is why it is difficult.
Smallpox is a fetal poison. It lies hidden in the body from the moment the body takes shape, and it breaks out when something sets it off. No one born can escape it. It may break out when a child catches a seasonal qi, or is chilled by wind and cold, or from food and drink, or from a fright. One illness leads to another, the harm takes many forms, and its changes cannot be foreseen. Besides, few cases go smoothly and many are dangerous. In some, a thousand remedies and a hundred plans cannot give one chance in ten thousand of recovery. That is why it is so hard [to treat].
- Chinese doctors held that smallpox came from a poison every child received in the womb. It lay hidden until something drew it out, and the illness then drove it from the body.
- Qi was the vital breath or energy that Chinese thinkers saw in the body and in the world. A seasonal qi was a harmful influence of the weather at a given time of year.
古有種痘一法起自江右達於京畿究其所源云自宋真宗時峨眉山有神人出為丞相王旦之子種痘而愈遂傳於世其説雖似渺茫然以理揆之實有參贊化育之功因時制宜之妙盖正痘感於得病之後而種痘則施於未病之先正痘治於成病之時而種痘則調於無病之日自表傳裏由裏達表既無諸證夾雜於其中復有善方引導於其外薫蒸漸染胎毒盡出又何慮乎為患多端變更莫測以致良工束手於無可如何之地耶此誠去險履平避危就安之良法也
Of old there is a method of planting smallpox, which arose from Jiangyou and reached the capital region. Inquiring into its source, it is said that in the time of Song Zhenzong a divine person came out of Mount Emei and planted smallpox for the son of the chancellor Wang Dan, who recovered; thereupon it was handed down in the world. Although the account seems vague and far off, yet measured by principle, it truly has the merit of assisting the transforming and nurturing [of Heaven and Earth], and the subtlety of fitting measures to the time. For natural smallpox is caught after one has fallen ill, while planted smallpox is applied before illness; natural smallpox is treated at the time the illness is formed, while planted smallpox is regulated on a day without illness. From the exterior it passes to the interior; from the interior it reaches the exterior; there are no [other] signs mixed in within, and there are good prescriptions guiding it from outside; steaming and gradually imbuing, the fetal poison all comes out. Then why worry about harm of many kinds and unfathomable changes, such that good physicians are bound hand [and foot] in a place where nothing can be done? This truly is a good method for leaving danger and treading the level, avoiding peril and approaching safety.
In the past there was a method of planting smallpox. It began in Jiangyou and spread to the capital region. As for where it came from, people tell a story from the time of Emperor Zhenzong of the Song. A holy man came out of Mount Emei and planted smallpox in the son of the chancellor Wang Dan, and the boy recovered. From then on it was handed down in the world. The story may seem far-fetched. But judged by reason, the method truly helps [Heaven and Earth] in their work of creating and nourishing life, and it wisely suits the treatment to the time. Natural smallpox is caught after one falls ill, but planted smallpox is given before any illness. Natural smallpox is treated when the illness has already taken hold, but planted smallpox is managed on a day when the child is well. [The seed's qi] passes inward from the surface, and [the poison] comes back out from inside to the surface. No other illnesses are mixed in, and good prescriptions guide it from outside. Steamed out little by little, the fetal poison comes out completely. Then why fear harm of many kinds and changes no one can foresee, which leave good doctors helpless? This is truly a fine method for leaving danger behind and walking on level ground, for avoiding peril and reaching safety.
- 種痘 zhongdou: giving a healthy child smallpox on purpose, from the scabs or fluid of a mild case, so that it would have a milder illness and never catch the disease again.
- Jiangxi province, in southeastern China.
- Zhenzong reigned 997–1022, more than seven hundred years before this book. Wang Dan (957–1017) was his chief minister.
- One of the four sacred mountains of Chinese Buddhism, in Sichuan, in western China.
然種痘一科多口傳心授方書未載恐後人視為虛誕之辭相沿日久無所考稽使至理良法竟置無用之地神功湮没豈不大可惜哉今将種痘一法細加研究審度精詳纂輯成書永垂千古庶為種痘之津梁咸登赤子於夀域也
But the specialty of planting smallpox has mostly been transmitted by mouth and taught heart [to heart]; prescription books have not recorded it. [We] fear later people will regard it as empty and absurd words; continuing so for a long time, there will be nothing to examine, causing the perfect principle and good method finally to be put in a useless place and its divine merit buried and lost. Would that not be greatly regrettable? Now we take the method of planting smallpox, study it in detail, examine and weigh it precisely and carefully, compile it into a book to hand down for a thousand ages, hoping it may be a ford and bridge for planting smallpox, and bring all red infants up into the realm of long life.
But planting smallpox has mostly been taught by word of mouth, from teacher to pupil, and medical books have not recorded it. We fear that later generations will take it for empty, foolish talk. If this goes on for long, there will be nothing to check it against. Then this perfect principle and good method will be cast aside as useless, and its wonderful power will be lost. Would that not be a great pity? So we have studied the method of planting smallpox in detail, weighed it carefully and precisely, and compiled it into a book to hand down for a thousand ages. We hope it will be a bridge for those who plant smallpox, and bring every infant safely to a long life.
嘗考種痘之法有謂取痘粒之漿而種之者有謂服痘兒之衣而種之者有謂以痘痂屑乾吹入鼻中種之謂之旱苗者有謂以痘痂屑濕納入鼻孔種之謂之水苗者然即四者而較之水苗為上旱苗次之痘衣多不應騐痘漿太渉殘忍故古法獨用水苗盖取其和平稳當也近世始用旱苗法雖㨗徑㣲覺迅烈若痘衣痘漿之説則斷不可從
I have examined the methods of planting smallpox. Some say take the fluid of the pox pustules and plant it; some say wear the clothes of a pox child and plant [so]; some say take pox-scab powder dry and blow it into the nose to plant, calling this the dry sprout; some say take pox-scab powder moist and put it into the nostril to plant, calling this the water sprout. But comparing these four, the water sprout is best, the dry sprout next; pox clothes mostly do not take effect; pox fluid is too cruel. So the ancient method used only the water sprout, taking its gentleness and safety. In recent times they began to use the dry sprout method; though quick and direct, it is felt to be slightly swift and violent. As for the pox-clothes and pox-fluid [methods], they must absolutely not be followed.
We have looked into the methods of planting smallpox. Some take the fluid from the pustules and plant that. Some dress a child in the clothes of a child with smallpox. Some grind the scabs to powder and blow it dry into the nose; this is called the dry seed. Some moisten the scab powder and put it into the nostril; this is called the water seed. Comparing the four, the water seed is best and the dry seed next. Smallpox clothes usually do not take, and smallpox fluid is too cruel. So the old method used only the water seed, because it is gentle and safe. In recent times people began to use the dry seed. It is quick and direct, but it is felt to be a little too fast and violent. As for smallpox clothes and smallpox fluid, those methods must never be followed.
- 苗 miao, literally “sprout” or “seedling”: the matter used to plant the pox, usually scabs from a child with a mild case.
夫水苗之所以善者以其勢甚和平不疾不徐漸次而入既種之後小兒無受傷之處胎毒有漸發之機百發百中㨗於影響盡善盡美可法可傳為種痘之最優者其次則旱苗雖烈猶與水苗之法相近兒體壮盛猶或可施
Now the reason the water sprout is good: because its force is very gentle, neither fast nor slow, entering by degrees. After it is planted, the child has no place of injury; the fetal poison has the opportunity of coming out gradually; a hundred shots, a hundred hits, quicker than shadow and echo; wholly good and wholly beautiful, to be taken as a model and handed down; it is the best of [ways of] planting smallpox. Next to it is the dry sprout; though violent, it is still close to the water-sprout method; if the child’s body is strong and robust, it may perhaps still be applied.
The water seed is good because it acts very gently. Neither fast nor slow, it enters little by little. After it is planted, the child suffers no harm, and the fetal poison has a chance to come out gradually. It succeeds every time, as surely as a shadow follows a body or an echo a sound. It is perfect in every way, a method to follow and hand down, the best way of planting smallpox. Next comes the dry seed. It is violent, but still close to the water-seed method, and it may be used if the child is strong and sturdy.
Left out of this excerpt.
種痘之時要細閲小兒氣血冲和臟腑均平内無痰熱食積所傷外無六淫之氣相侵方可用上好痘痂種之一嵗者用二十餘粒三四嵗者用三十餘粒置於淨磁鍾内以栁木作杵碾為細末以淨水滴三五㸃入鍾内春温用冬熱用乾則再加水幾㸃總以調匀為度不燥不濕用新棉些須攤極薄片裹所調痘屑在内揑成棗核様以紅線拴定仍留寸許長則剪去将苗納入鼻孔分男左女右不可離人時時㸔守倘小兒用手拈弄急禁止之或被𡁲出急将苗塞鼻内不可稍緩恐洩苗氣下苗後必以六個時辰為度然後取出如遇天氣嚴寒多留數刻若遇時令和暖早取數刻亦可要在臨時斟酌痘苗取出之後其苗氣漸次而入傳遍五藏至七日始𤼵熱發熱三日而苗見見苗三日而出齊出齊三日而灌漿漿足三日而回水結痂大功成矣
At the time of planting smallpox, one must examine closely [that] the small child’s qi and blood are harmonious and the viscera evenly balanced; inside, no harm from phlegm-heat or food accumulation; outside, no qi of the six excesses invading; only then may one use top-quality pox scabs to plant it. A one-year-old uses twenty-odd grains; a three- or four-year-old uses thirty-odd grains. Put them in a clean porcelain cup, make a pestle of willow wood, and grind them to fine powder; with clean water drip three to five drops into the cup; spring: use [it] warm; winter: use [it] hot; if dry, then add a few more drops of water; in all, take evenly mixed as the measure, not dry, not wet. Use a little new cotton, spread into an extremely thin sheet, wrap the mixed pox powder inside, pinch it into the shape of a jujube pit, fasten it with red thread, still leaving about a cun; [what is] long, cut off. Put the sprout into the nostril, dividing male left, female right. One must not leave [the child]; constantly watch and guard. If the child takes it with the hand and plays with it, urgently stop it; if it is sneezed out, urgently stuff the sprout into the nose; one must not delay even slightly, fearing the sprout qi leaks. After placing the sprout, one must take six shichen as the measure, then take it out. If meeting severe cold weather, leave it several ke more; if meeting a mild and warm season, taking it out several ke early is also possible; the essential lies in weighing it at the time. After the pox sprout is taken out, its sprout qi gradually enters and passes through all five organs; at the seventh day fever first breaks out. Fever three days, then the sprouts [spots] appear; spots appear three days, then they come out evenly [are complete]; complete three days, then they fill with fluid; fluid full three days, then the water returns and scabs form; the great work is accomplished.
At the time of planting, examine the child closely. Its qi and blood must be in harmony and its organs in balance. Inside, it must not be troubled by phlegm, heat, or undigested food. Outside, it must not be under attack from the qi of the six excesses. Only then plant it, using the best scabs. For a child of one year, use twenty-some pieces of scab; for a child of three or four, thirty-some. Put them in a clean porcelain cup and grind them to a fine powder with a willow-wood pestle. Drip three to five drops of clean water into the cup, warm in spring and hot in winter. If the mixture is dry, add a few drops more. What matters is to mix it evenly, neither dry nor wet. Spread a little new cotton into a very thin sheet, wrap the mixed scab powder in it, and pinch it into the shape of a jujube pit. Tie it with red thread, leaving about an inch of thread, and cut off the rest. Put the seed into the nostril, the left for a boy and the right for a girl. Someone must stay with the child and watch it all the time. If the child plays with the seed, stop it at once. If the child sneezes it out, put it back in the nose at once, without the least delay, or the seed’s qi may leak away. Once the seed is in, leave it for six double hours, then take it out. In bitter cold, leave it in a little longer; in mild, warm weather, it may come out a little earlier. The point is to judge at the time. After the seed is taken out, its qi enters little by little and passes through all five organs. On the seventh day, fever begins. After three days of fever, the spots appear. Three days later, all the spots are out. Three days after that, they fill with fluid. Three days after they are full, the fluid dries up and they form scabs, and the great work is done.
- The six excesses were wind, cold, summer heat, damp, dryness, and fire: kinds of harmful qi from the weather that doctors thought could invade the body from outside.
- Chinese inches (cun). A Qing cun was a little longer than an English inch.
- The left side belonged to yang and to males, the right to yin and to females, so boys and girls were treated on opposite sides.
- The Chinese day was divided into twelve double hours (shichen), so six double hours made half a day.
- The five organs were the heart, liver, spleen, lungs, and kidneys. The next section of the book, left out here, traces the seed’s qi from the nose to the lungs and on through the other four.
旱苗種法用銀管約長五六寸曲其頸碾痘痂極細納於管端按男左女右對凖鼻孔吹入之至七日而亦𤼵熱今時多用此法蓋取其簡便㨗入不致脱落而有透洩苗氣之患也苐恐後人用之不善輕吹之則不驟入重吹之則迅烈難當且恐流涕過多苗隨涕去往往不騐今欲垂法後世當取其法之和平稳當萬全者而則效之此所以獨取於水苗也
The dry-sprout planting method: use a silver tube about five or six inches long, bend its neck; grind the pox scabs very fine and put [the powder] in the end of the tube; following male left, female right, aim it accurately at the nostril and blow it in; by the seventh day there is likewise fever. Nowadays this method is much used, because it is simple and convenient, enters quickly, and does not lead to falling out with the trouble of the sprout’s qi leaking away. But [we] fear later people will use it badly: blown lightly, it does not enter at once; blown heavily, it is swift and violent and hard to bear; and [we] fear [that with] too much running of the nose, the sprout goes away with the mucus, and often it does not take. Now, wishing to hand down a method to later ages, one should take the method that is gentle, safe, and wholly secure and follow it. This is why we take only the water sprout.
For the dry-seed method, use a silver tube about five or six inches long, bent near the end. Grind the smallpox scabs very fine and put the powder in the end of the tube. Aim it carefully at the nostril, the left for a boy and the right for a girl, and blow the powder in. By the seventh day there is fever, [as with the water seed]. Many people use this method nowadays. It is simple and quick, and the seed cannot fall out and let its qi escape. But we fear that later people will use it badly. Blown too lightly, the powder does not go in at once; blown too hard, it acts too fast and violently for the child to bear. Then too, if the nose runs too much, the seed washes out with the mucus, and often it does not take. Since we wish to hand down a method to later ages, we should choose the gentle, safe, and wholly reliable one and follow it. That is why we choose only the water seed.
小兒出痘者當長漿漿足之時則彼痘氣充盛取其貼身裏衣與未出痘之兒女服之服二三日夜間亦不脱下至九日十一日始𤼵熱此乃衣傳然恐氣薄不透多有不熱不出其法不靈故不可用
When a child having smallpox is at the time of growing fluid, when the fluid is full, then its pox qi is abundant; take its inner clothes worn next to the body and give them to a boy or girl who has not had smallpox to wear; wear them two or three days, at night too not taking them off; by the ninth or eleventh day fever begins. This is transmission by clothes. But [we] fear the qi is thin and does not penetrate; often there is no fever and [the pox] does not come out; the method is not effective, so it may not be used.
When a child with smallpox reaches the stage when the pustules fill with fluid, and they are full, its smallpox qi is at its strongest. Take the shirt that child wears next to the skin, and have a boy or girl who has not had smallpox wear it for two or three days, without taking it off at night. On the ninth or eleventh day, fever begins. This is passing it on by clothing. But we fear the qi may be too thin to get through. Often there is no fever and no pox comes out. The method is unreliable, so it must not be used.
擇小兒出痘之順者取其痘漿以棉拭之分男左女右塞入鼻中亦能發痘但取痘漿之時不令本家知覺揑破痘漿盜以作種使彼真氣宣洩毒不能解此忍心害理不仁之事也同志者切宜深惡而痛絶之又豈可尤而效之也哉
Choose a child whose smallpox comes out smoothly, take its pox fluid, wipe it with cotton, and, dividing male left and female right, stuff it into the nose; it too can bring out the pox. But at the time of taking the pox fluid, without letting the family know, [people] pinch and break the pustules and steal [the fluid] to make seed, causing that [child’s] true qi to leak out, so that the poison cannot be resolved. This is a hard-hearted, unprincipled, inhumane thing. Those of like mind should earnestly hate it deeply and cut it off utterly; how could they blame it and yet imitate it?
Choose a child whose smallpox is going smoothly. Wipe up the fluid from its pustules with cotton, and put the cotton into the nose, the left for a boy and the right for a girl. This too can bring out the pox. But when they take the fluid, people pinch the pustules open without the family knowing, and steal it to use as seed. This lets the sick child’s true qi leak out, so that its poison cannot be cleared. It is a cruel, wrong, and inhumane thing to do. All who agree with us should hate it deeply and put a complete stop to it. How could anyone condemn it and then do it himself?
Questions a reader might ask, with short answers and the sections they rest on. Checked in a separate review.
What happens
Where did smallpox come from, according to the editors?
From a fetal poison that every child carries from the womb. It lies hidden until something sets it off, such as a seasonal qi, cold, food, or a fright.
Read section [1]
Where did planting smallpox begin?
The editors say it began in Jiangyou (Jiangxi) and spread to the capital region. They repeat a story that a holy man from Mount Emei planted smallpox in the son of the chancellor Wang Dan under Emperor Zhenzong of the Song, but admit the story seems far-fetched.
Read section [2]
What are the four ways of planting smallpox, and how do the editors rank them?
Fluid from the pustules, the clothes of a sick child, dry scab powder blown into the nose, and moistened scab powder put into the nostril. The water seed is best and the dry seed next; the clothes usually do not take, and the fluid method is too cruel.
Read section [4]
How was the water seed prepared and used?
Twenty-odd pieces of scab for a one-year-old, thirty-odd for a child of three or four, were ground in a porcelain cup with a willow pestle, mixed with a few drops of water, wrapped in thin cotton shaped like a jujube pit, tied with red thread, and put into one nostril for six double hours while someone watched the child.
Read section [7]
Thinking further
Why do the editors think planted smallpox is safer than the natural disease?
It is given on a day when the child is well, before any illness, with no other sickness mixed in and good prescriptions to guide it, so the fetal poison comes out gently and completely.
Why did the editors want to write the method down?
Planting had been taught mostly by word of mouth and was missing from medical books. They feared later generations would dismiss it as foolish talk and the method would be lost.
Read section [3]
What do the editors object to in the fluid method?
People broke open a sick child's pustules without the family knowing and stole the fluid. The editors believed this let the sick child's true qi leak out so that its own poison could not be cleared, and they call it cruel and inhumane.
Read section [10]
Who and what this source names, in the original. Each name links to every source in the library that mentions it. Not yet checked.
Ideas
- Inoculation Giving a healthy person smallpox on purpose, from the scabs or matter of a mild case, so that the illness would be mild and never come again. Chinese, Ottoman and African practitioners knew it before it was tried in Boston and London in the 1720s. Sections [2], [3], [4].
- Qi (氣) The vital breath or energy that Chinese thinkers saw in the body and in the world. Sections [1], [7].
- Smallpox An infectious disease that begins with fever and leaves pitted scars. It was unknown in the Americas until Europeans arrived, and it struck Mexico and Michoacán in 1520; most historians identify the Japanese epidemic of 735–737 as smallpox too. Sections [1].
- The womb poison (胎毒) The Chinese medical teaching that smallpox came from a poison every child received in the womb, which lay hidden until something drew it out. Sections [1], [2].
- Yin and yang (陰陽) Paired forces, such as dark and light or cold and heat. Scholars and doctors alike held that when they left their proper places, or the seasons came out of order, sickness followed. Sections [7], [8], [10].
People
- Emperor Zhenzong of Song (宋真宗) Emperor of the Song dynasty, in whose reign, a story said, smallpox inoculation began. Sections [2].
- Wang Dan (王旦) Chief minister to Emperor Zhenzong, whose son, the story said, was the first to have smallpox planted. Sections [2].
Places
- Beijing The capital of the Qing dynasty, where court physicians compiled the medical encyclopedia that describes smallpox inoculation in 1742. Sections [2].
- Jiangxi A province of southern China, where, the Qing court physicians wrote, the planting of smallpox began. Sections [2].
- Mount Emei A sacred mountain in Sichuan, known for its Buddhist temples and hermits, from which, the story went, a holy man came to plant smallpox in a minister's son. Sections [2].
Page images of the original object or of the printed edition, from the libraries and archives that hold them. The pages shown are copied here where the holder marks them public domain; titles link to the holder's own viewer. Click a page to see it full size.
Yuzuan Yizong jinjian, juan 60, Wenyuan ge Siku quanshu manuscript copy (about 1778)
Zhejiang University Library volume, scanned by the China Academic Digital Associative Library (CADAL); on Wikimedia Commons. leaves 5a–7a, 15b–16b, 17b–18b (file pages 6–10, 27–29, 31–33). Public domain (Wikimedia Commons: PD-old).
The copy our text follows, read against these page images. The library record does not say whether the volume is the manuscript or a photographic reprint of it; its pages match the digital text line for line.
Yuzuan Yizong jinjian, juan 60–64, Shanghai: Commercial Press, 1912
Wikimedia Commons (scan, SSID 13376350). juan 60, pp. 1–6 (file pages 3–8). Public domain (published 1912).
A later printing, used to collate our text; it agrees in every kept word.
Difficulty: Challenging, dense medical prose; the fetal poison, qi, and yin and yang need the notes, but the step-by-step methods are easy to follow.
Fits these units
- Case study: smallpox. How did a terrifying disease become the only one ever eradicated? (Once in a Lifetime)
- From inoculation to vaccine. How did a new way to prevent smallpox spread, and why did people resist it? (Innovation in History)
Key terms
- qi
- the vital breath or energy that Chinese thinkers saw in the body and the world
- yin and yang
- paired opposite forces, such as dark and light or cold and heat, whose balance was thought to keep the body healthy
- inoculation
- giving a healthy person smallpox on purpose, from the matter of a mild case, so that the illness would be mild and never come again
- pustule
- a raised spot on the skin filled with fluid
- scab
- the dry crust that forms over a healing spot or wound
- compendium
- a large book that gathers the knowledge of a whole subject
- chancellor
- the emperor’s chief minister
Questions
- Comprehension
What four ways of planting smallpox do the editors describe? Which do they rank first and second, and why do they reject the other two?
- Analysis
The editors argue that planted smallpox is safer than catching it naturally. What reasons do they give? Which rest on what doctors could see, and which on ideas about the fetal poison and qi?
- Analysis (reliability)
The editors admit the method was known only from a story and had been taught mostly by word of mouth, and they also say the dry method they ranked second was widely used in their day. What does this suggest about how far an official book like this shows what ordinary doctors actually did?
- Connection
Read Lady Mary Wortley Montagu's Engrafting against Smallpox and Edward Jenner's Instructions for Vaccine Inoculation. Compare how the matter is put into the body in each, what each writer says makes the method safe, and what Jenner’s cowpox changed.
Activity
Students turn the water-seed method into a one-page instruction card for a doctor in 1742, keeping only steps the text gives. In a second column they note, for each step, the reason the editors give or the idea behind it (qi, the fetal poison, yin and yang, or careful watching). They then set the card beside Jenner’s Instructions for Vaccine Inoculation and list what stayed the same and what changed.
A printable worksheet for this source · More on Hearth Learning
New translation from the Classical Chinese text of the Yizong jinjian (1742), juan 60, in the Wenyuan ge manuscript copy of the Siku quanshu (about 1778), leaves 5a–7a, 15b–16b, and 17b–18b. About a sixth of the juan is included: the introduction, the first section (without its closing list of topics), and the sections on the water seed, dry seed, clothing, and fluid methods.
Terms: 痘 dou is “smallpox”; 種痘 zhongdou is “planting smallpox”; 苗 miao (literally “sprout”) is “seed”; 正痘 is “natural smallpox.” Qi is left untranslated.
- Original
- Text as printed in the named edition or on the object, read from page images. Edition: Yuzuan Yizong jinjian 御纂醫宗金鑑 (completed 1742), juan 60, 編輯㓜科種痘心法要㫖, leaves 5a–7a, 15b–16b and 17b–18b, Wenyuan ge 文淵閣 manuscript copy of the Siku quanshu 四庫全書 (about 1778). Digital text: Kanseki Repository KR3e0090, base edition WYG, extracted by code (the Kanseki text’s variant 苖 is printed as 苗, as in both scans), read against page images of the Wenyuan ge copy and collated with the Commercial Press printing (Shanghai, 1912).
- Transliterated
- Machine transliteration (pinyin), generated by script, not reviewed
- Close English
- Close translation drafted by Claude (Anthropic), kept as a working draft
- Simplified English
- Drafted by Claude (Anthropic) from the original and checked unit by unit against the original in a separate review, then compared with earlier translations and tested for borrowed wording.
- Editor’s review
- Not yet.
- Specialist review
- Not yet. Readings a specialist should confirm are listed for later review.
- Rights
- Original: public domain. Edition: public domain. Our translations and notes: CC BY-SA 4.0; credit “Hearth Library, hearthinteractive.com” with a link.
Sources for the notes
- Yuzuan Yizong jinjian 御纂醫宗金鑑. Juan 60, leaves 5a–7a, 15b–18b, with the table of contents of the juan; the Siku editors’ note (提要, dated Qianlong 43, 1778) and the memorials of 1739 in the opening juan (首卷), for the compilation and Wu Qian; juan 34 and 77, for the six kinds of harmful qi from the weather. Wenyuan ge Siku quanshu manuscript copy. Digital text: Kanseki Repository, KR3e0090. Page images of juan 60: China Academic Digital Associative Library scan (Zhejiang University Library copy), on Wikimedia Commons.
- Yuzuan Yizong jinjian 御纂醫宗金鑒. Juan 60–64. Shanghai: Commercial Press, 1912. Juan 60, pp. 1–6, for collation. Scan on Wikimedia Commons.
- Tuotuo 脫脫 et al. Song shi 宋史 (History of the Song). Juan 6 and 8 (annals of Zhenzong) and juan 282 (biography of Wang Dan). Wenyuan ge Siku quanshu copy. Digital text: Kanseki Repository, KR2a0032.
- Huangdi neijing Suwen 黃帝內經素問, with Wang Bing’s commentary. Juan 2, “Yin yang ying xiang da lun.” Sibu congkan text. Digital text: Kanseki Repository, KR3e0001.
- Zuozhuan 左傳. Duke Xi 24 and Duke Xiang 21 (尤而效之). Digital text: Kanseki Repository, KR1e0001.
- Liji 禮記, “Zhongyong” 中庸 (贊天地之化育). Digital text: Kanseki Repository, KR1d0052.
- Ch’iu Chung-lin 邱仲麟. “Smallpox Inoculation in Ming-Qing China: Regional Spread, Knowledge Dissemination, and Bacterin Production.” Bulletin of the Institute of History and Philology, Academia Sinica 77, no. 3 (2006): 451–516. Abstract.
- Guan, Linyu, Shenjia Gu, Yunhai Pan, Lance E. Rodewald, and Chuanxi Fu. “Variolation Techniques, Medical Explanations, and Dissemination in Late Imperial China.” Emerging Infectious Diseases 32, no. 10 (2026): 1677–1685.
- Lockhart, William. The Medical Missionary in China: A Narrative of Twenty Years’ Experience. London: Hurst and Blackett, 1861. Pages 120–121 (Alexander Pearson and vaccination at Canton) and 238–242 (Chinese inoculation).
- “Mount Emei.” Encyclopaedia Britannica online.
- Horniman Museum and Gardens, London. Bamboo foot rule (chi), object 4758xvi.2; incense timekeeping spirals marked in shichen, object 15.69. Online catalogue records.